Feb 11

Blowfish venom is more powerful than cobra venom?

Cobra venom: Toxicity is a nerve poison, it will cause pain, swelling, high blood pressure, nausea, abdominal pain, drowsiness, limb paralysis, coma and ultimately death. If bitten, after 15-30 minutes, there is no drug treatment, the victim will die.

Blowfish venom: Blowfish is one of nature’s most poisonous animals, their body contains tetrodotoxin. It is more poisonous than potassium cyanide. Under normal circumstances, a little bit of this neurotoxin is sufficient to paralysis an adult within several minutes. Eating this toxic food, the man will feel unwell mind dizziness, numb mouth, until the fall to the ground, whole body spasm, breath and at last will die.

Blowfish venom is more powerful than cobra venom?  No one has done the exact comparison tests, and there are many types of cobra and blowfish. Toxicity of those are also different, it is very difficult to compare their toxicity. As the above data, two kinds of toxins are very powerful.

Feb 11

The supply of cobra venom

We(ChongQing JinLei ShiPin Trade Co.,Ltd)provide a wide variety of snake venoms(lyophillized venom), including Agkistrodon acutus venom,Naja naja atra venom(cobra venom), Bungarus multicinctus venom, Bungarus fasciatus venom, Vipera russelli venom, Agkistrodon blomhoffii venom, Ophiophagus hannah venom, Trimeresurus stejnegeri venom, Trimeresurus mucrosquamatus venom, Agkistrdon halys venom, Thailand Naja naja atra venom. These snake venoms directly from snake farm of China. The quality is in conformity with export standards of snake venom. The certificate will be issued by China Import and Export Commodity Inspection Bureau or by any of its branches.At the same time,we will provide you with competitive prices.

If you want to buy snake venom or want more information ,you can send mail to  linduzai@hotmail.com , please feel free to contact us.

E-mail / MSN :venomforsale@hotmail.com
Tel:  Mobile:+86 18723390447
PERSON CONTACTED: Pitter Lin

Feb 10

How serious the toxicity of sea snake venom

Without exception, all sea snakes are poisonous snakes, but the severity of toxicity is different with each other.  Sea snake venom contains neurotoxic like cobra venom, but the strange thing is that it play a major role in skeletal
muscle, so it is called ciguatera.

Due to the complex composition of the sea snake venom, Most of the sea snake venom is harmful to people’s every organ, and may affect every cell, the cardiovascular system, respiratory and nervous systems. Some people think that the toxic of sea
snake vneom is 50 times more than toxic of cobra venom or is 80 times more than toxic of sodium cyanide. It is estimated
that 3.5 mg (dry weight) long-beaked sea snake venom, which  is not the most poisonous in the sea snake,  is enough to kill an adult,
this is only one-fifth of lethal dose of cobra venom. Sea snakes do not generally take the initiative to attack humans
. According to the 120 cases of snake bites, the fishermen is bit by sea snake venom when  the fishermen picked  the fish and
dived. Therefore, sea snake would seriously threaten to human. In coastal areas of Thailand, Vietnam and India,it often reported
that Some people have often been bit by sea snake.

Feb 09

Sea snake venom

China’s waters are known to have 15 kinds of sea snakes, for example, Lacticande semifasciata. Venoms from this sea snake have highly
toxic and is much bigger than those from the most poisonous snake on land. Because of its venom is a mixture of a variety of proteins,
freeze-dried venom of the sea accounts for about 90% of peptides, including enzymes, peptides, small peptides. After a structural analysis,
it was found that the short peptide chain of sea snake venom neurotoxin is composed of   60 -62 amino acid residues and four disulfide . Long polypeptide chain is composed of  66-74 amino acids residues and 5 disulfide bonds. They combine the high specificity acetylcholine receptors, blocking synaptic
transmission, mainly blocking cholinergic neuromuscular joints, causing paralysis, mostly respiratory muscle paralysis and
suffocation. It has been demonstrated that a variety of sea snake venom have a common antigen. Anti-snake venom serum, such as cleft chin sea of anti-snake venom toxins, can Offset 7-8 species of sea snake toxins, but also a variety of venoms from snakes on land, such as viper venom, cobra, king cobra snake
venom and so on. Therefore, sea snake antitoxin serum have High value and can cure snake bites in clinical treatment. Sea snake
wine can promote blood circulation and pain relief, commonly used for rheumatism pain and waist pain according to Traditional
Chinese Medicine. Although enzyme content of sea snake venom is less than those of snake on land. The venom of pit viper from
Dalian Snake Island is a ready-made L-arginine esterase (the fiber coagulation-like enzyme). It has achieved good results for treatment of vascular thrombosis disease and ischemic cerebrovascular disease.
Does the sea snake venom have the same effect?

With the depth of marine drugs research, sea snake venom will prove to be the precursor of marine drug material, and better
serve the cause of human health.

Feb 02

Snake Venom Protein May Inhibit Tumor Growth

   Researchers of the American Chemical Society are using found a protein from copperhead snake venom can slow breast tumor growth. The protein blocks tumor cell adhesion and invasion and inhibits new blood vessel development in the tumors. Researchers from Australia are using snake venom to cure cancer.

1:SVT(snake veom toxin) would inhibit the growth of AICAP

According to a article from Molecular Cancer Therapeutics, snake venom has positive effects for inhibiting the growth of AICAP. The molecular was on nuclear factor, an anti-apoptotic transcriptional factor that can activate AICAP cell. The scientists treated AICAP cells with SVT for 24 hours, and then assessed their growth and found it slow the activation of NF-b which can speed up cancer cell growth.

2: Australian found snake venom can slow Tumor growth.

According to the anti-cancer research hold by Australian, the researchers found that a compound from snake venom can destroy cells that contribute to supplying blood and nutrients to tumours.
“What we’ve found that’s quite interesting to us is that the level of material that’s required, that is the concentration of material that’s required, is much lower than we would have expected normally,” Associate Professor Tony Woods said.
“In fact, at the levels we’re using these compounds seem to affect the blood vessels that supply tumours only and not normal blood vessels.”

In the near future, more and more drugs which is used to cure cancer are from the snake venom.

Feb 02

Russell’s viper venom alter the morphology of erythrocytes

In the present investigation, it was found that the biconcave erythrocytes became sphero-echinocytes.Phospholipase A2 could also produce the sphero-echinocytosis. The phospholipase A2 inhibitor, p-bromophenacyl bromide reduced the degree of RVV sphero-echinocytosis. Verapamil, which is a phenylalkylamine calcium channel blocker, could not prevent the RVV sphero-echinocytosis. Although antivenom could not reverse the RVV sphero-echinocytosis, these effects  were minimized. Phospholipase A2 lead to the RVV sphero-echinocytosis, Calcium and some plasma factors are required for this process. Early treatment with antivenom has 
positive effects for prevention of RVV sphero-echinocytosis, which may reduce hypoxic cell injury. The effects of Russell’s viper venom (RVV) on human erythrocytes
 is about the erythrocyte morphology. 
The maximal effect was detected at 800 ng of venom. Morphology changed  immediately at 1 minute and the change 
reached maximum at 30 minutes. The mild degree of erythrocyte deformation was observed at 60 and 120 min with 
100 ng of RVV. Venom at various dosages ranging from 50 ng to 120 micrograms increased hematocrit significantly.
 When EDTA was used as an anticoagulant or when plasma was substituted by isotonic saline, acetar, albumin added
 acetar solutionThere were no morphologic changes .